Tooth-Binding Micelles for Dental Caries Prevention

Tooth-binding micelles for dental caries prevention.

Maintenance of the effective local concentration of antimicrobials on the tooth surface is critical for the management of cariogenic bacteria in the oral cavity. We report on the design of a simple tooth-binding micellar drug delivery platform that would effectively bind to tooth surfaces. To achieve tooth-binding ability, the chain termini of biocompatible Pluronic copolymers were modified wit...

Deciduous Tooth and Dental Caries

In humans, deciduous tooth development begins before birth and is complete by about the fourth postnatal year. They are lost when the patient becomes 11 years old. The permanent teeth appear by 6-7 years (and later for the wisdom teeth). Most are successional, and a few are non successional. The coronal part of the human tooth is composed of two hard tissues: enamel and dentin, and this part in...

Dental Caries – A Strategic approach for prevention

Dental caries is a chronic, bio-behavioural disease that extends throughout the life span of human beings. Prevention of dental caries includes measures to prevent the occurrence of disease, such as risk factor reduction, but also to arrest the progress of disease and reduce consequences of the disease once it is established. Preventive measures like fluoride therapy and pit and fissure sealant...

The Prevention of Dental Caries

Diagnosis and Prevention Strategies for Dental Caries

Dental caries is one of the oldest and most common diseases found in humans. With the recent shift from the surgical model, which emphasized restorative treatment, to a medical model of disease management, newer strategies emphasize disease prevention and conservation of tooth structure. For early detection and monitoring of caries, rather than waiting until a cavity is formed and restorative t...